“These studies involve humans where they give them 180, 200 grams of fructose in a day. Within a couple weeks, they would have many metabolic issues. But this would not happen when these individuals received that level of fructose but had its metabolism blocked by simply giving them a gout pill called allopurinol. I want to mention parenthetically that quercetin as a nutritional supplement works almost as effectively as allopurinol. I mentioned earlier, it targets the same enzyme called xanthine oxidase. One study in 22 young men with mild elevation of their uric acid over eight weeks giving them 500 milligrams a day of quercetin dropped their uric acid by about 8%, just in eight weeks. So you’re targeting that enzyme involved in the manufacturing of uric acid.”

Levels, How Uric Acid Drives Weight Gain, Disease and More